PT-141 / Bremelanotide

Bremelanotide is a synthetic cyclic peptide and melanocortin-receptor agonist. 'PT-141' material sold online should not be assumed equivalent to a regulated medicine.

Licensed use — if any

FDA-authorised Vyleesi treats acquired, generalised hypoactive sexual desire disorder in premenopausal women after other causes are excluded. It is not authorised to improve sexual performance and is not indicated for men.

Research interest

Central melanocortin signalling and sexual-desire disorders in carefully defined populations.

Evidence lens

Known does not mean proven for everything.

The strongest claim on the page should never be stronger than the strongest source behind it.

What we can say

A regulated US medicine exists for a tightly defined HSDD indication.
The FDA label explicitly excludes performance enhancement and use in men or postmenopausal women.
Research material and a licensed auto-injector are not interchangeable products.

What remains unknown

Identity and bioequivalence of non-regulated PT-141 products.
Benefit–risk outside the authorised population.
How online combination protocols change safety.

Risk and caution

The FDA label includes transient blood-pressure increases, heart-rate reduction, nausea and focal hyperpigmentation.
It is contraindicated in uncontrolled hypertension or known cardiovascular disease.
A clinician-led assessment is essential for any legitimate prescription pathway.

Regulatory snapshot

Jurisdiction and context matter.

Not presented here as a UK-authorised treatment. Verify any current UK product through the MHRA database.

FDA-authorised prescription medicine for a narrow HSDD indication in premenopausal women.

Tested sport

No sporting clearance is given. Athletes should check the exact medicine and current WADA/Global DRO status.

Primary sources

Open the record.

Statuses change. Always check the current regulator, product label, trial record and anti-doping list.

This is not medical advice.

Do not start, stop or source a medicine based on this page. Speak to a qualified healthcare professional and use regulated supply routes. Call 999 in an emergency or NHS 111 for urgent advice.

Continue through the library →