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Synthetic melanocortin analogue

Melanotan II

An unapproved melanocortin analogue promoted online for tanning and sexual effects, often through products with uncertain identity and purity.

01

Licensed use — if any

No authorised tanning, libido or erectile-dysfunction indication is established. It is not the same as the regulated afamelanotide implant.

02

Research interest

Melanocortin signalling, pigmentation and sexual-function observations, without an approved consumer product.

Evidence lens

Known does not mean proven for everything.

The strongest claim on the page should never be stronger than the strongest source behind it.

What we can say
  • No regulated cosmetic tanning indication exists.
  • FDA's safety-risk summary cites serious published case reports.
  • Online vial presentation adds identity, sterility and dosing uncertainty.
What remains unknown
  • A reliable long-term cancer and cardiovascular risk profile.
  • Actual composition of grey-market products.
  • Safety of repeated or combined use.
Risk and caution
  • FDA cites case reports including melanoma, posterior reversible encephalopathy syndrome, sympathomimetic toxidrome and priapism.
  • Aggregation, immunogenicity and peptide impurities are additional concerns.
  • Changing moles or persistent erections require urgent medical assessment.

Regulatory snapshot

Jurisdiction and context matter.

UK

Not presented as a UK-authorised medicine or cosmetic tanning product. Suspect online medicine sales can be reported to MHRA.

US

Not FDA approved; listed by FDA among bulk substances presenting significant safety concerns.

Tested sport

No sporting clearance is implied. Check the current WADA list and exact product.

Primary sources

Open the record.

Statuses change. Always check the current regulator, product label, trial record and anti-doping list.

  1. 01FDA · peptide compounding safety risks
  2. 02MHRA · report a suspicious online medicine seller
  3. 03EMA · authorised afamelanotide product
This is not medical advice.

Do not start, stop or source a medicine based on this page. Speak to a qualified healthcare professional and use regulated supply routes. Call 999 in an emergency or NHS 111 for urgent advice.

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